5-(3-bromophenyl)-3-methyl-1H-pyrazole hydrochloride
3-(3-bromophenyl)-5-methyl-1H-pyrazole hydrochloride
CAS: 324054-75-3
Molecular Formula: C10H9BrN2
5-(3-bromophenyl)-3-methyl-1H-pyrazole hydrochloride - Names and Identifiers
5-(3-bromophenyl)-3-methyl-1H-pyrazole hydrochloride - Physico-chemical Properties
| Molecular Formula | C10H9BrN2 |
| Molar Mass | 237.1 |
| Density | 1.50 |
| Melting Point | 101～104℃ |
5-(3-bromophenyl)-3-methyl-1H-pyrazole hydrochloride - Introduction
3-(3-bromophene)-5-methyl-1H-pyrazole hydrochloride is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C10H9BrClN2
-Molecular weight: 277.55g/mol
-Melting point: 172-175 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents (such as methanol, ethanol)
Use:
- 3-(3-bromophenyl)-5-methyl-1H-pyrazole hydrochloride is used as a pharmaceutical intermediate in the pharmaceutical field.
-It is used in the synthesis of pyrazole drugs, pesticides and anti-tumor drugs.
Method:
- 3-(3-bromophenyl)-5-methyll-1h-pyrazole hydrochloride has many preparation methods, one of which is as follows:
1. First, 3-bromobenzoic acid and acetylacetone are subjected to a condensation reaction under an alkaline condition to obtain 3-(3-bromophenyl)-3-phenylpropanone.
2. The above product is then reacted with hydrazine to give 3-(3-bromophenyl)-5-methyl-LH-pyrazole.
3. Finally, the resulting pyrazole compound is reacted with hydrochloric acid to give 3-(3-bromophenyl)-5-methyl-1H-pyrazole hydrochloride.
Safety Information:
-The compound may be harmful to the human body and the environment, so you need to pay attention to safety during operation.
-Contact with skin and eyes may cause irritation, so be careful to avoid contact.
-When using, you should pay attention to protective measures, such as wearing gloves, goggles and protective clothing, and ensure that the operation is carried out in a well-ventilated place.
-Observe local regulations when disposing of waste and dispose of it properly.
Nature:
-Appearance: White solid
-Molecular formula: C10H9BrClN2
-Molecular weight: 277.55g/mol
-Melting point: 172-175 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents (such as methanol, ethanol)
Use:
- 3-(3-bromophenyl)-5-methyl-1H-pyrazole hydrochloride is used as a pharmaceutical intermediate in the pharmaceutical field.
-It is used in the synthesis of pyrazole drugs, pesticides and anti-tumor drugs.
Method:
- 3-(3-bromophenyl)-5-methyll-1h-pyrazole hydrochloride has many preparation methods, one of which is as follows:
1. First, 3-bromobenzoic acid and acetylacetone are subjected to a condensation reaction under an alkaline condition to obtain 3-(3-bromophenyl)-3-phenylpropanone.
2. The above product is then reacted with hydrazine to give 3-(3-bromophenyl)-5-methyl-LH-pyrazole.
3. Finally, the resulting pyrazole compound is reacted with hydrochloric acid to give 3-(3-bromophenyl)-5-methyl-1H-pyrazole hydrochloride.
Safety Information:
-The compound may be harmful to the human body and the environment, so you need to pay attention to safety during operation.
-Contact with skin and eyes may cause irritation, so be careful to avoid contact.
-When using, you should pay attention to protective measures, such as wearing gloves, goggles and protective clothing, and ensure that the operation is carried out in a well-ventilated place.
-Observe local regulations when disposing of waste and dispose of it properly.
Last Update：2024-04-09 21:01:54
